Hormonal treatment for breast cancer

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Hormone therapies may also be called endocrine therapies. The endocrine system in the body makes hormones. When these hormones attach to special proteins called hormone receptors, the cancer cells with these receptors grow.

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Breast cancer is a malignant tumor that begins and grows in the breast. Malignant tumors can grow and invade nearby tissues or travel to distant organs. This progression is called metastasis.

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Hormonal therapy is used to treat any stage of hormone-receptor-positive breast cancer or to reduce the risk of developing it or having a recurrence. Hormonal therapy can be used by both pre- and postmenopausal women. Hormonal therapy can be given before, at the same time as, or after other breast cancer treatments.

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Hormone therapy to treat breast cancer uses drugs or treatments to lower levels or block the action of female sex hormones estrogen and progesterone in a woman's body. This helps slow the growth of many breast cancers. Hormone therapy makes cancer less likely to return after breast cancer surgery. It also slows the growth of breast cancer that has spread to other parts of the body.

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What is hormone therapy? Who is given hormone therapy? When is hormone therapy given?

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Some types of breast cancer are affected by hormones in the blood. ER-positive and PR-positive breast cancer cells have receptors proteins that attach to estrogen, which helps them grow. There are different ways to stop estrogen from attaching to these receptors.

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Hormones like estrogen and progesterone are chemicals produced by glands in the body. Normally, these hormones help regulate body cycles, like menstruation. However, sometimes these same hormones can cause cancer to grow.

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If you're struggling to find what you need, call our Support line on 7 days a week, 8am-8pm. Hormonal therapy blocks the effects of oestrogen on breast cancer cells and reduces the risk of breast cancer coming back. Back to Treating.

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The treatment of breast cancer is driven by subtype classification, of which the assessment of hormone receptor status is one of the important determinants of therapy. In this review, we will describe the classification of hormone receptor status and the various endocrine treatment strategies. Opportunities for personalization of care are illustrated.

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This critical review focuses on the role of steroid hormones and their receptors in the development and treatment of breast cancer, with special reference to estrogen receptors, as well as mechanisms of receptor-ligand interactions, response or resistance to hormonal therapy against breast cancer, in conjunction with other modalities like surgery and chemotherapy. Tamoxifen is used in hormonal treatment of breast cancer for up to five years, depending on the presentation. However, there have been recent developments in hormonal therapy of breast cancer in the last ten years, with the introduction of many different alternative therapies for this condition.

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